No. 20 Kansas State (-2.5) at Iowa State (7:30 p.m. 17 TCU (-6.5) at No. Accountability Time: After a terrible 10-21 showing against the spread in Week 4, we rallied with a 16-11 record this past week, including correctly projecting the outright upsets by Arizona State, Michigan and Mississippi State. Tennessee's Joe Milton III has had quite the journey during his college career. USC at UCLA pick: The computer favors Southern Cal by a 60.5 percent margin over the rival Bruins to stay in the Pac-12 title hunt, but watch . This year's Red River Rivalry might not be that nationally relevant, but it should be a fun one, per usual. Sean Tucker I Rich Barnes USA Today Sports, Drake Maye I Grant Halverson/Getty Images, Watch more top videos, highlights, and B/R original content, J.J. McCarthy I Gregory Shamus/Getty Images, Jordan Travis I Melina Meyers/USA Today Sports, Do Not Sell or Share My Personal Information. They gave up 322 rushing yards in the loss to Oregon State two weeks ago, and Utah has averaged better than 6.0 yards per carry in three of its four games. But Oklahoma has held each of its five opponents to 100 rushing yards or fewer. 2 Georgia (5-0) at No. ET: Baylor 32, Oklahoma 23, Georgia State at Southern Miss, 3 p.m. ET: San Diego State 23, UNLV 18, Houston at SMU, 7 p.m. The major factor for this matchup is the Bulldogs defense giving Georgia the better overall talent edge, since Tennessee has had trouble against the pass this season. Photo by Steph Chambers/Getty Images It looks like they'll keep a position there since they're playing a Memphis team that's on a three-game losing streak, had a 1-4 record in October and has fielded one of the worst defenses in the AAC. Penn State has lost two of its last three games, which is discouraging, but the recent competition has been fierce. Taulia Tagovailoa, the younger brother of Miami Dolphins QB Tua Tagovailoa, has had a decent season. 2021 Week 6 Matchups. Arizona State is searching for its next head coach, while UCLA is back near the top of the college football world. ET: Boston College 27, Duke 24, Kentucky at Missouri, Noon ET: Kentucky 31, Missouri 23, Minnesota at Nebraska, Noon ET: Minnesota 26, Nebraska 18, Iowa at Purdue, Noon ET: Purdue 23, Iowa 17, Western Kentucky at Charlotte, Noon ET: Western Kentucky 31, Charlotte 14, Maryland at Wisconsin, Noon ET: Maryland 28, Wisconsin 27, Georgia Tech at Virginia Tech, 12:30 p.m. 20 UCLA all lost to unranked foes. The Tigers would have a good chance to keep the streak alive if they were playing basically anyone other than Alabama in their division. 14 Ole Miss (-6.5). The Jayhawks moved to 5-0 after beating Iowa State 14-11 last week. 7 min read. Kansas State looks like one of the best teams in the Big 12, having upset Oklahoma 41-34 and beating Texas Tech 37-28 in back-to-back weeks. Ole Miss has won the last three straight over Vanderbilt. Quarterback Bo Nix has played great for Oregon with the help of first-year offensive coordinator Kenny Dillingham. However, they keep trying for some reason, averaging more than 27 rushing attempts per game. ET: Coastal Carolina at UL Monroe, 8 p.m. Ole Miss trailed Alabama 35-0 before making the final score (42-21) a little bit more respectable. After an exciting opening weekend of college football, we have an idea of who the elite contenders are for the 2022 season. And the kicker: Ohio State is 6-0 in this series with an average margin of victory of 36.0 points since Maryland joined the Big Ten. 14 NC State (-3) (8 p.m. Prediction: Washington 48, Arizona State 13, No. Mike Norvell looks like he finally has this FSU offense figured out, and quarterback Jordan Travis looks strong so far this season. Prediction: Kansas State 28, Iowa State 21, No. 25 Cincinnati (-17) covers at Temple in a 4 p.m. Georgia Tech (2-3) at Duke (3-2), 12:30 p.m. The Crimson Tide know that it's time to hit the gas if they want to be playing for the national championship. I like Maryland at home here, but I think Purdue keeps it close. There were a few bad beats, but I can't describe my picks as anything other than terrible last week. No. Two offenses with the ability to regularly put the ball in the end zone will face off in Salt Lake City this weekend. Georgia State enjoyed an out-of-nowhere offensive surge in a 46-14 Week 5 win over UL Monroe, but the Panthers should come crashing back . The Black Knights are 1-3, with their only win coming in Week 3 over FCS squad Villanova. Unfortunately, quarterback Spencer Sanders has been digressing each week throughout the season so far. Penn State won't be a riser after a win against Indiana, unless it demolishes the Hoosiers on the road. Despite losing 49-3 in Week 1 to Georgia, the Ducks have rebounded nicely and are 4-1. Enjoy the free college football picks against the spread as well! 23 Mississippi State vs. Arkansas, Noon ET. (Miami (Fla.) at Florida State, 3:30 p.m. Aside from USC, UCLA is the last remaining undefeated team in the Pac-12. 13 Arkansas.The . ET, FS1), No. 19 Wake Forest (5-0) at Syracuse (3-2), 3:30 p.m. The Cowboys opened conference play with a 36-25 victory over Baylor last week. ET: North Texas 17, FIU 16, Troy at Louisiana, 5 p.m. 14 Illinois, 3:30 p.m. ET. The Panthers were another team with high expectations heading into the season, but transfer QB Kedon Slovis and Co. have sputtered to 4-4. No. This is another contest that won't be close. Prediction: Ohio State 56, Michigan State 13. Arizona's poor defense that gives up 475 yards per game won't be able to stop the Utes. They have gone a combined 1-3 over the last two weeks, but a rivalry like this one will always have some juice. UCF may be on the road, but a game at Memphis never hurt anybody. Oklahoma State hosts Texas Tech, and Kansas State visits Iowa State on the same day. The Wolfpack would be booted from the Top 25 if they're dominated by the Demon Deacons at home. Here are five questions that need to be answered this week and our Week 6 predictions. The Wildcats are just a two-point favorite going on the road to Ames. One of the most explosive teams in the nation is headed to Athens to face the defending champion Georgia Bulldogs. No. The Beavers are 6-2, with their only downfalls coming against Utah and USC. Maryland's 4-0 start to the season blew up in spectacular fashion at home against Iowa in a game in which the Terrapins committed seven turnovers. We will have 6 more Premium Picks against the spread this week! One of the college picks the model is high on in Week 6: Auburn (+28.5) stays within the spread when it faces No. Neither Notre Dame nor Virginia Tech has looked particularly good on offense yet this season, save for the first three quarters of Notre Dame's opener against Florida State in which Jack Coan looked like a Heisman Trophy contender. He played in 13 games over three . Sam Hartman and this Wake offense, which is putting up 40.4 points per game, should have no problems against an Army defense that ranks 102nd nationally. Vegas Houston -6.5 College Football Game Picker Houston by 12.58. The 2021 college football season is underway. No. 2 Tennessee. 17 Ole Miss covers as a six-point favorite against No. 17 Iowa. ET . ET, Fox), South Carolina at No. ET: South Carolina 34, Vanderbilt 23, JMU at Louisville, 7:30 p.m. See draftkings.com/sportsbook for full terms and conditions. 11 Utah for prediction. Unfortunately the Buckeyes will hand Sparty its fourth-straight loss of the season on Saturday. A bye for 'Cuse comes before a tough schedule ahead, including games vs. NC State, at Clemson and vs. Notre Dame for the rest of the month. ET: Bowling Green 30, Western Michigan 21, UTEP at Rice, 7 p.m. Georgia averages 41.8 points and allows just 10.5 points per game. The wait is finally over. ET: Given the respective schedules thus far, I'm not buying either of these teams as a threat to win the Mountain West Conference. Premium Picks are made public once the games are played. 17 TCU, Noon ETSee No. That seemed impossible after their Week 0 meltdown in the loss to Illinois, but the Cornhuskers gave both Oklahoma and Michigan State a serious run for their money on the road and won their other three games (Fordham, Buffalo and Northwestern) by a combined score of 136-17. Still, one is going to pick up its fifth win of the season, and it will probably be Air Force. This one is pretty hard to pick, since both of these teams are similarly matched and have comparable bodies of work through five weeks. Ole Miss will likely have more success running the ball in Week 6 than it did in Week 5, and I'm not suggesting that Matt Corral is going to get shut out. Both of these offenses boast a pair of talented quarterbacks. That streak will continue this weekend when Indiana is unable to find any yards on the ground and has trouble scoring. That has enabled them to win back-to-back contests against ranked opponents (Kansas State and Baylor). There's trap games every week and Tulane is going to get caught in one this weekend. NCAA football predictions and Week 6 Opening Line Report with Best Bets and Picks by expert college football handicappers at Docsports.com. 1 Alabama (5-0) at Texas A&M (3-2), 8 p.m. The 2022 College Football Week 6 will feature Tennessee Vs LSU and Texas Tech Vs Oklahoma St. We will have 6 more Premium Picks against the spread this week! Meanwhile, Michigan's once-dominant rushing attack has tapered off considerably as of late, held below 3.0 yards per carry by both Rutgers and Wisconsin. It was surprising, given that Georgia's offense scored 30 or more points in each game prior. Records: The Bear . They turned it around with back-to-back wins to get to 5-3, and the victory against Liberty should be another solid building block. The Tigers have won 10 straight against Boston College. Still, Washington can still make some noise in the Pac-12 this season. Although the order has changed somewhat, Alabama, Georgia, Ohio State, Clemson and Michigan have remained perfect through five weeks. 2020's meeting was a 53-45 shootout that the Sooners won. This week, Liberty earned a spot in the Top 25 for the first time this season, but it looks like that will be short-lived. 115: Baylor Bears 29.1. NFL expert picks, predictions, lines for Week 2 highlighted by the Los Angeles Chargers vs Kansas City, Miami at Baltimore, and Minnesota at Philadelphia. The Buckeyes need to be dominant in this matchup to continue to show the selection committee just how good they are, and they'll be exactly that. Two disappointing teams will face off in College Station for what was projected to be an important game in SEC title picture prior to the start of the season. ", Rather, it's: "How many upsets will there be?". In just the second meeting of top five teams . 11 Utah (-3.5) at No. ET. In each of the past seven years, the regular-season meeting between Oklahoma and Texas was decided by a single possession. Head coach Brian Kelly and the Tigers started the season slow with a loss in Week 1, but it's been mostly positive from there. 5 Clemson at Boston College, 7:30 p.m. The Fighting Irish can't run the ball, and the Hokies needed a punt-return touchdown just to reach 21 points in their most recent game against Richmond. They were inches from defeating the Trojans and have continuously put away teams that they're favored against. Even if the Chants decide to be nice and focus primarily on running the ball (and the clock), you're still talking about an offense that averages 6.4 yards per carry against a defense that just allowed 503 rushing yards in a 59-33 loss to Georgia Southern. At long last, we've reached the #Pac12AfterDark on a Friday night portion of the regular season, and what a fantastic game to get that party started. Jalon Daniels, who has had 11 touchdown passes in four weeks, threw for just 93 yards on 14 pass attempts. ET: Tulane 30, ECU 27, Tulsa at Navy, 3:30 p.m. ET. I think Notre Dame's offense will be too much for this BYU defense, which allows 335.4 yards per game. Vanderbilt (+38.5) over GEORGIA. And aside from Notre Dame picking off basically everything in the fourth quarter against Wisconsin, neither defense has been all that special, with each allowing more yards per play on defense than it has gained on offense. Call (877-8-HOPENY) or text HOPENY (467369). Arkansas lost 37-0 to Georgia. This would've been a very exciting matchup with a healthy Devin Leary, who's out for the year with a torn pec. Quarterback Cameron Rising will lead Utah to their seventh win of the season. 24 Oregon State at Washington, Friday, 10:30 p.m. 5 Clemson (-20.5) at Boston College (7:30 p.m. He has over 100 rushing yards in every game this season. ET (Friday). ET: Memphis 34, Houston 17, Colorado State at Nevada 10:30 p.m. Jay Biggerstaff/Getty Images, Watch more top videos, highlights, and B/R original content, Dorian Thompson-Robinson. The Orange have decent wins against Purdue and Louisville, but the formula for stopping them has become clear. ET on ESPNU, live stream on fuboTV (Start your free trial)Missouri gave Georgia a serious scare last week, leading the Bulldogs for most of that game. The Flames are 7-1, with their best wins coming against BYU and Southern Miss. ET: Nebraska 28, Rutgers 17, Houston at Memphis 7:30 p.m. ET: Nevada 24, Colorado State 10, UNLV at San Jos State, 10:30 p.m. 10 BYU (5-0) vs. Boise State (2-3), 3:30 p.m. TCU's Max Duggan has yet to throw an interception this season, and he had three touchdown passes in the last two weeks. ET: UTEP 27, Rice 23, Appalachian State at Coastal Carolina, 7:30 p.m. 15 Wake Forest (-15) (7:30 p.m. The line is moving steadily in the Rebels' favor despite UK getting elite rusher Chris . But Penn State has yet to cough up the ball more than once in a game and has an impressive plus-six mark of its own. Undefeated Tennessee comes into this one boasting one of the country's most explosive offenses. The latest in the sports world, emailed daily. College football Week 5 picks, predictions against the spread. They're led by a quality defense that forces turnovers. ET. TCU aided in that process by obliterating the Sooners in Week 5. NC State fell 30-20 to Clemson last week, and Florida State suffered its first loss to Wake Forest last week. He has added another 255 yards and three scores on the ground, too. No. ET: This one is compelling because it's a chance for Oregon State to become an AP Top 25 team for the first time in more than eight years. 7 in the AP poll for that one, but they were down 24-0 in the blink of an eye. It was definitely a "burn the tape" game for Oklahoma State since it had Sanders for most of the contest. Week 6 of the college football schedule is here, and it's time to make our picks and predictions for the top games on Saturday. I think this one will be close for awhile before Tennessee pulls away in the fourth. This prime-time clash in Blacksburg fits the bill for Week 6. ET, SEC Network), Army at No. And back in 2008, the unranked Hawkeyes upset No. No. Prediction: Ohio State 52, Northwestern 16, No. It's the middle of the week in November . 16 Penn State at Indiana, 3:30 p.m. 4 Penn State won 21-19 on a walk-off touchdown at unranked Iowa. Coastal Carolina Vs Arkansas St. At this point, the question isn't: "Will there be upsets? The Cowboys had one their worst games in recent memory, losing to Kansas State 48-0 on the road. This all depends on the health of Oklahoma State quarterback Spencer Sanders. The Horned Frogs can afford a high concession or two because their offense is averaging 549.5 total yards per game, which is 129 yards above Kansas' average. Oklahoma's Eric Gray has 460 yards and three scores. 20 Wake Forest at No. ET, East Carolina (3-2) at UCF (2-2), 6 p.m. 21 Texas (4-1), Noon ET (in Dallas). Awesome if you enjoy low-scoring, late drama, that is. Kamari Lassiter. NC State is just a 3.5-point favorite at home, but it'll be interesting to see how this Wolfpack team rebounds from the home loss to Clemson. After one of the best starts in program history, they've lost three straight conference games. 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